Haldane's Dilemma

What is Haldane's Dilemma?

What is the Substitution Cost?

What Does ReMine Say About Haldane's Dilemma?

Solutions to Haldane's Dilemma

  There may not be a Dilemma

  The Cost of Beneficial Substitutions and Soft Selection

  Multiple Simultaneous Substitutions Lower the Cost Even Further

  Kimura on the Substitution Cost as Evidence for the Neutral Theory

  Ewens Answers Kimura's Objections

  Quotes from Sewall Wright and Others that Support Ewens' Claims

Future Directions

Conclusion

Bibliography

Earlier Version of this Page

The Evolution Evidence Page

Please e-mail me (Robert Williams rwms@gate.net) with suggestions, comments, or criticisms.